Rifagut 400 Mg (Rifaximin)

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In Stock

$105.00$250.00

Tablet/s PriceQuantity
100 Tablet/s $105.00
200 Tablet/s $185.00
300 Tablet/s $250.00

Description

Rifagut 400 mg, is a medication commonly prescribed for certain infections and gastrointestinal conditions. Here’s a detailed, pointwise breakdown of everything you might need to know about Rifagut 400 mg:

General Information

  1. Generic Name: Rifaximin
  2. Brand Name: Rifagut
  3. Strength: 400 mg per tablet
  4. Manufacturer: Various pharmaceutical companies

Composition and Mechanism

  1. Active Ingredient: Rifaximin 400 mg.
  2. Class: Antibiotic, specifically a rifamycin derivative.
  3. Mechanism of Action:
    • Rifaximin binds to the beta-subunit of bacterial DNA-dependent RNA polymerase, inhibiting bacterial RNA synthesis.
    • This action leads to the death of bacteria, effectively treating infections.
    • It has a broad-spectrum activity against gram-positive and gram-negative bacteria, as well as anaerobic bacteria.

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How to use Rifagut 400 Mg?

  1. Traveler’s Diarrhea: Caused by non-invasive strains of Escherichia coli.
  2. Hepatic Encephalopathy: To reduce the risk of recurrence in adults.
  3. Irritable Bowel Syndrome with Diarrhea (IBS-D): Particularly useful for patients whose symptoms are predominantly diarrhea.
  4. Small Intestinal Bacterial Overgrowth (SIBO): Helps reduce the bacterial load in the intestines.

Rifagut 400 Mg Dosage and Administration

  1. Traveler’s Diarrhea:
    • Adults: 200 mg three times a day for 3 days.
  2. Hepatic Encephalopathy:
    • Adults: 550 mg twice daily.
  3. Irritable Bowel Syndrome with Diarrhea:
    • Adults: 550 mg three times daily for 14 days.
  4. Route of Administration: Oral, taken with or without food.

Pharmacokinetics

  1. Absorption: Poorly absorbed from the gastrointestinal tract, with minimal systemic absorption.
  2. Distribution: Primarily remains in the gut lumen.
  3. Metabolism: Metabolized minimally in the liver.
  4. Excretion: Excreted mainly in feces.

What are the Side Effects of Rifagut 400 Mg?

  1. Common Side Effects:
    • Nausea
    • Dizziness
    • Headache
    • Abdominal pain
    • Flatulence
  2. Serious Side Effects:
    • Severe allergic reactions (rash, itching/swelling, severe dizziness, trouble breathing)
    • Persistent diarrhea (may indicate a severe intestinal condition such as Clostridium difficile-associated diarrhea)
    • Signs of liver problems (nausea/vomiting that doesn’t stop, stomach/abdominal pain, yellowing eyes/skin, dark urine)

Precautions and Warnings

  1. Allergic Reactions: History of hypersensitivity to Rifagut 400 Mg or any rifamycin antibiotics.
  2. Liver Function: Use with caution in patients with severe liver impairment.
  3. Antibiotic Resistance: Prolonged use may result in the overgrowth of non-susceptible organisms.
  4. Clostridium Difficile-Associated Diarrhea (CDAD): Consider in all patients with diarrhea following antibiotic use.
  5. Pregnancy and Breastfeeding: Consult a healthcare provider as data on use during pregnancy and lactation are limited.

Drug Interactions

  1. P-Glycoprotein Inhibitors: May increase rifaximin exposure.
  2. Other Antibiotics: Concurrent use with other antibiotics may alter the effectiveness of rifaximin.
  3. Warfarin: Monitoring of blood coagulation parameters is advised due to potential interaction.

Storage

  1. Temperature: Store at room temperature, between 20-25°C (68-77°F).
  2. Conditions: Keep away from moisture and light. Do not store it in the bathroom.
  3. Packaging: Keep in a tightly closed container.

Other Pills: 

Rifagut 200 Mg | Azicip 250 Mg | Azicip 500 | Azeetop 500 Mg | Azeetop 250 Mg | Azeetop 1000 Mg

Additional information

Tablet/s

100 Tablet/s, 200 Tablet/s, 300 Tablet/s

Active Ingredient (Generic Name):

Rifaximin

Manufacturer:

Sun Pharmaceutical Industries Ltd

Packaging:

10 tablets in 1 strip

Strength:

400mg

Delivery Time:

6 To 15 days

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