Cephadex DT 250 Mg (Cephalexin)

Description

What is a Cephadex DT 250 Mg?

Cephadex DT 250 mg is a broad-spectrum antibiotic that belongs to the cephalosporin class of antibiotics. It is commonly use to treat various bacterial infections by inhibiting the growth and multiplication of bacteria. The “DT” in the name stands for “dispersible tablet,” indicating that it can dissolve in water for easier ingestion, particularly useful for patients who have difficulty swallowing pills.

Which is the Active Ingredient in Cephadex DT?

The active ingredient in Cephadex DT 250 mg is Cefalexin (also spell Cephalexin), a first-generation cephalosporin antibiotic. Cefalexin is know for its effectiveness against a variety of Gram-positive and some Gram-negative bacteria.

Mechanism of Action

Cefalexin works by disrupting the synthesis of the bacterial cell wall. It binds to specific penicillin-binding proteins located inside the bacterial cell wall, inhibiting the final transpeptidation step of peptidoglycan synthesis. This results in a weakened cell wall that ultimately leads to bacterial cell lysis and death.

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Indications and Uses of Cephadex DT?

Cephadex DT 250 mg is prescribe for the treatment of several types of bacterial infections, including but not limite to:

• Respiratory tract infections (e.g., bronchitis, pneumonia)
• Urinary tract infections (e.g., cystitis, pyelonephritis)
• Skin and soft tissue infections (e.g., cellulitis, abscesses)
• Otitis media (middle ear infections)
• Bone infections (e.g., osteomyelitis)

Cephadex DT 250 Mg Dosage and Administration

• Standard Dosage: The usual adult dose is 250 mg every 6 hours. Alternatively, 500 mg may give every 12 hours.
• Pediatric Dosage: Dosage for children is typically based on body weight, often 25-50 mg/kg/day in divided doses.
• Administration: The tablet can be disperse in a small amount of water and consume immediately. It’s essential to follow the prescribe dosage regimen strictly to avoid resistance development.

Contraindications

Cephadex DT 250 mg should not use in individuals with:

• A known allergy to cephalosporins or any component of the formulation.
• Severe allergic reactions (e.g., anaphylaxis) to penicillins, due to possible cross-reactivity.

Precautions and Warnings

• Allergic Reactions: Cephalosporins can cause severe allergic reactions, including anaphylaxis. It’s crucial to inform healthcare providers about any history of allergic reactions to antibiotics.
• Renal Impairment: Dosage adjustments may be necessary for patients with impaired kidney function.
• Clostridium difficile-associated Diarrhea (CDAD): Prolonged use of antibiotics can lead to an overgrowth of Clostridium difficile, resulting in severe diarrhea.

What are the Side Effects of Cephadex DT 250 Mg?

Common side effects of Cephadex DT 250 mg include:

• Gastrointestinal disturbances (nausea, vomiting, diarrhea)
• Allergic reactions (rash, itching, hives)
• Dizziness and headache
• Rare but severe side effects include pseudomembranous colitis, anaphylaxis, and Stevens-Johnson syndrome.

Drug Interactions

Cephadex DT 250 mg may interact with other medications, such as:

• Probenecid: Increases and prolongs serum concentrations of cefalexin.
• Warfarin: Enhanced anticoagulant effect, leading to an increased risk of bleeding.
• Metformin: Co-administration may lead to higher plasma concentrations of metformin, increasing the risk of side effects.

Pregnancy and Lactation

• Pregnancy: Cephadex DT 250 mg is generally considere safe for use during pregnancy. However, it should only be used when need and prescribe by a healthcare provider.
• Lactation: Cefalexin is excreted in breast milk in small amounts. Caution is advised, and breastfeeding mothers should consult their healthcare provider.

Overdose

In case of an overdose, symptoms may include nausea, vomiting, epigastric distress, diarrhea, and hematuria. Immediate medical attention is required, and supportive measures should be implemented.

Storage

Cephadex DT should store at room temperature, away from moisture, heat, and direct light. Keep out of reach of children.

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