Azee 250 mg (Azithromycin)

Description

What is Azee 250 mg?

Azee 250 mg is an antibiotic medication containing Azithromycin, a macrolide antibiotic. It is used to treat various bacterial infections by inhibiting bacterial protein synthesis.

Mechanism of Action:

Azithromycin binds to the 50S ribosomal subunit of bacteria, inhibiting protein synthesis. This prevents bacteria from growing and replicating, ultimately killing the bacteria.

Indications:

• Respiratory Infections: Treats conditions like pneumonia, bronchitis, and sinusitis.
• Ear Infections: Effective for otitis media.
• Skin Infections: Useful for skin and soft tissue infections.
• Sexually Transmitted Infections: Prescribed for chlamydia and gonorrhea.
• Throat Infections: Used for pharyngitis and tonsillitis.

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Azee 250 mg Dosage and Administration:

• Standard Dose: Typically, 250 mg once daily for 3-5 days.
• Pediatric Dose: Dosage is based on body weight; usually, 10 mg/kg on the first day, followed by 5 mg/kg on subsequent days.
• Administration: Taken orally, with or without food. It’s advisable to take the medication at the same time each day.

Pharmacokinetics:

• Absorption: Rapidly absorbed from the gastrointestinal tract.
• Distribution: Widely distributed throughout the body tissues.
• Metabolism: Partially metabolized in the liver.
• Excretion: Excreted mainly in bile and to a lesser extent in the urine.

What are the Side Effects of Azee 250 mg?

• Common: Nausea, vomiting, diarrhea, abdominal pain, and headache.
• Rare: Allergic reactions, liver enzyme alterations, and hearing disturbances.
• Serious: Severe allergic reactions, liver dysfunction, and QT prolongation (a heart rhythm disorder).

Precautions:

• Allergies: Do not use if allergic to Azithromycin or other macrolide antibiotics.
• Liver Disease: Use with caution in patients with liver impairment.
• Heart Conditions: Patients with a history of arrhythmia should use it cautiously.
• Pregnancy and Breastfeeding: Consult a healthcare provider as it crosses the placenta and is excreted in breast milk.

Drug Interactions:

• Antacids: Can reduce absorption; take Azee at least 1 hour before or 2 hours after antacids.
• Warfarin: May increase the risk of bleeding.
• Other Antibiotics: Avoid using other macrolides to prevent additive effects.

Contraindications:

Known hypersensitivity to Azithromycin, erythromycin, or any macrolide or ketolide antibiotic.

Azee 250 mg Overdose:

• Symptoms: Severe nausea, vomiting, diarrhea, and hearing loss.
• Management: Symptomatic and supportive treatment; no specific antidote.

Storage:

Store at room temperature, away from light and moisture. Keep out of reach of children.

Other Pills: 

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