Fenofibrate 145 mg

Description

What is Fenofibrate 145 mg?

Fenofibrate 145 mg is a medication primarily prescribed to manage high cholesterol and triglyceride levels in the blood. This medication belongs to a class of drugs known as fibrates, which work by reducing the amount of fat produced by the liver. High levels of cholesterol and triglycerides can lead to atherosclerosis (hardening of the arteries), which increases the risk of heart disease, stroke, and other cardiovascular problems. Fenofibrate is a lipid-lowering agent that falls under the category of fibrates. It is typically available in tablet form, with 145 mg being a standard dose. Fenofibrate is used to treat high cholesterol and triglycerides, particularly in patients who have not responded adequately to lifestyle changes alone (like diet and exercise). Let’s explore fenofibrate 145 mg in detail, covering its uses, how it works, potential side effects, interactions, and more.

How Does Fenofibrate 145 mg Work?

• Mechanism of Action: Fenofibrate works by activating peroxisome proliferator-activated receptor alpha (PPARα), a protein that plays a crucial role in lipid metabolism. This activation increases the breakdown of fatty acids and reduces the production of triglycerides in the liver.
• Lipid Profile Improvement: By lowering triglyceride levels, fenofibrate also helps to increase levels of high-density lipoprotein (HDL or “good” cholesterol) and reduce low-density lipoprotein (LDL or “bad” cholesterol).

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Who Should Take Fenofibrate 145 mg?

• Indications: Fenofibrate is typically prescribe for adults with primary hypercholesterolemia (high cholesterol) or mixed dyslipidemia (abnormal levels of cholesterol and triglycerides) who are at risk for cardiovascular events and have not achieved desired lipid levels through diet and exercise alone.
• Contraindications: Fenofibrate should not take by individuals with severe liver or kidney disease, gallbladder disease, or those who are allergic to fenofibrate or any of its components.

How to Take Fenofibrate 145 mg?

• Dosage Instructions: The standard dose is one 145 mg tablet per day, taken with or without food. It’s essential to follow your healthcare provider’s instructions regarding the dosage.
• Consistency: Try to take fenofibrate at the same time each day to maintain an even level of the medication in your blood.
• Missed Dose: If you miss a dose, take it as soon as you remember. If it’s almost time for the next dose, skip the missed dose. Do not double up on doses.

What are the Potential Side Effects of Fenofibrate 145 mg?

• Common Side Effects: These may include headache, back pain, nausea, and elevated liver enzymes. Some people might experience abdominal pain or digestive issues.
• Serious Side Effects: Although rare, fenofibrate can cause serious side effects such as myopathy (muscle pain or weakness), rhabdomyolysis (a severe muscle condition), liver damage, or pancreatitis. If you experience unexplained muscle pain, tenderness, or weakness, especially if accompanied by fever or malaise, contact your doctor immediately.
• Monitoring: Regular monitoring of liver and kidney function, as well as lipid levels, is recommended while taking fenofibrate to ensure the medication is working as intended and not causing harm.

Drug Interactions

• Statins: Caution is advised when taking fenofibrate with statins (another class of cholesterol-lowering drugs) due to an increased risk of muscle-related side effects.
• Blood Thinners: Fenofibrate can enhance the effects of blood thinners like warfarin, leading to an increased risk of bleeding. Your doctor may need to adjust your dosage of blood thinners.
• Other Medications: Always inform your healthcare provider of all the medications you are taking, including over-the-counter drugs, vitamins, and herbal supplements, as they can interact with fenofibrate.

Precautions and Warnings

• Liver and Kidney Function: Patients with a history of liver or kidney issues should use fenofibrate cautiously, as it can exacerbate these conditions.
• Pregnancy and Breastfeeding: Fenofibrate is not recommended during pregnancy or breastfeeding unless necessary. Discuss potential risks with your doctor.
• Alcohol Consumption: Limit alcohol intake while on fenofibrate, as it can increase triglyceride levels and risk of liver damage.

Lifestyle and Dietary Considerations

• Dietary Adjustments: While on fenofibrate, it’s crucial to maintain a low-fat, low-cholesterol diet to maximize the medication’s effectiveness.
• Exercise: Regular physical activity can help improve your lipid profile and overall cardiovascular health, complementing the effects of fenofibrate.
• Weight Management: Achieving and maintaining a healthy weight can further reduce triglyceride levels and improve cholesterol.

Other Pills: 

Fenofibrate 160 mg | Trulicity Injection 1.5mg | Trulicity Injection 0.75 | Rybelsus 14 mg | Rybelsus 7 mg

What to Expect with Fenofibrate 145 mg

• Onset of Action: You may start to see improvements in your lipid levels within a few weeks of starting fenofibrate, but full effects can take up to two months.
• Regular Check-Ups: Your doctor will likely schedule regular blood tests to monitor your cholesterol levels and ensure the medication is working effectively without causing adverse effects.

Stopping Fenofibrate

• Do Not Discontinue Abruptly: Do not stop taking fenofibrate without consulting your healthcare provider, as it can lead to a rebound effect, causing your cholesterol and triglyceride levels to rise sharply.

FAQs

Can I take fenofibrate with other cholesterol-lowering medications?

• Yes, fenofibrate can take with other cholesterol-lowering medications like statins, but this combination increases the risk of muscle-related side effects. Always consult your doctor before combining these drugs.

What should I do if I experience muscle pain while taking fenofibrate?

• If you experience unexplain muscle pain, tenderness, or weakness, contact your doctor immediately. This could be a sign of a serious condition known as rhabdomyolysis, which requires prompt medical attention.

How long will I need to take fenofibrate?

• Fenofibrate is often prescrib as a long-term treatment to manage cholesterol and triglyceride levels. Your doctor will determine the duration of treatment based on your individual needs and how well you respond to the medication.

Where Can I Buy a Fenofibrate 145 mg?

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