Androl 50 (oxymetholone)

Description

What is an Androl 50 Tablet?

Androl 50 Tablet, also known by its chemical name oxymetholone, is a potent anabolic steroid. It was initially develop in the 1960s by the pharmaceutical company Syntex. Its primary medical uses are to treat certain types of anemia and muscle-wasting conditions.

What is Androl 50 Chemical Composition and Structure?

• Chemical Formula: C21H32O3
• Molecular Weight: 332.48 g/mol
• Structure: It is a synthetic derivative of dihydrotestosterone (DHT), modified to enhance its anabolic properties while minimizing androgenic effects.

What are the Androl 50 Tablet Uses?

• Anemia Treatment: Oxymetholone stimulates erythropoiesis, the production of red blood cells, which helps combat various forms of anemia, including aplastic anemia, myelofibrosis, or hypoplastic anemia caused by chemotherapy.
• Muscle Wasting: It is prescribing for patients suffering from severe muscle wasting due to chronic diseases like HIV/AIDS, helping to improve muscle mass and strength.

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What is Androl 50 Tablet Dosage and Administration?

• Typical Dosage: For anemia, the recommended dosage is 1-5 mg/kg of body weight per day. For muscle wasting, dosages may vary based on the specific condition and patient response, often starting around 50-100 mg daily.
• Administration: Oxymetholone is taking orally in the form of tablets, typically with meals to minimize gastrointestinal discomfort.

Mechanism of Action:

Oxymetholone works by binding to androgen receptors, promoting protein synthesis and nitrogen retention in muscles, leading to significant increases in muscle mass and strength. It also enhances the production of erythropoietin, a hormone crucial for red blood cell production.

What are the Side Effects of Androl 50 Tablet?

• Common Side Effects:
  • Gastrointestinal issues like nausea, vomiting, and diarrhea.
  • Increased or decreased libido.
  • Headaches.
• Serious Side Effects:
  • Hepatotoxicity: Liver damage, including conditions like cholestatic hepatitis, peliosis hepatis, and hepatocellular carcinoma.
  • Cardiovascular issues: Increased risk of heart disease, high blood pressure, and changes in cholesterol levels.
  • Psychological effects: Mood swings, aggression, and depression.
• Androgenic Side Effects: In men, potential for testicular atrophy, gynecomastia, and infertility. In women, virilization symptoms such as deepening of the voice, increased body hair, and clitoral enlargement.

Contraindications:

• Liver Disease: Due to its hepatotoxic nature, oxymetholone should not uses by individuals with pre-existing liver conditions.
• Prostate Cancer: Androgenic effects can exacerbate prostate cancer.
• Pregnancy and Breastfeeding: It is contraindicated due to potential teratogenic effects and negative impact on fetal development.

Abuse and Misuse of Androl 50 Tablet:

• Bodybuilding: Despite medical regulations, oxymetholone is often misused by bodybuilders and athletes to rapidly increase muscle mass and strength. This off-label use is illegal and dangerous.
• Dependence and Withdrawal: Long-term misuse can lead to dependence. Discontinuation may result in withdrawal symptoms such as fatigue, depression, and loss of muscle mass.

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